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1

Overcoming drug resistance to receptor tyrosine kinase inhibitors: learning from lung cancer

Kuwano, Michihiko, Sonoda, Kahori, Murakami, Yuichi, Watari, Kosuke, Ono, Mayumi

Journal:

Pharmacology & Therapeutics

Year:

2016

Language:

english

File:

PDF, 1.32 MB

english, 2016

2

Is nuclear expression of Y box-binding protein-1 a new prognostic factor in ovarian serous adenocarcinoma?

Toshiharu Kamura, Hideaki Yahata, Satoshi Amada, Shinji Ogawa, Takanori Sonoda, Hiroaki Kobayashi, Masamune Mitsumoto, Kimitoshi Kohno, Michihiko Kuwano, Hitoo Nakano

Journal:

Year:

1999

Language:

english

File:

PDF, 315 KB

english, 1999

3

Expression of multidrug-resistance-associated protein (MRP) and chemosensitivity in human gastric cancer

Kazuya Endo, Yoshihiko Maehara, Tetsuya Kusumoto, Yuji Ichiyoshi, Michihiko Kuwano, Keizo Sugimachi

Journal:

International Journal of Cancer

Year:

1996

Language:

english

File:

PDF, 818 KB

english, 1996

4

New nortriterpenoid isolated from anti-rheumatoid arthritic plant, Tripterygium wilfordii, modulates tumor growth and neovascularization

Shin Ushiro, Mayumi Ono, Juichiro Nakayama, Tadami Fugiwara, Yasuhiro Komatsu, Keizo Sugimachi, Michihiko Kuwano

Journal:

International Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 241 KB

english, 1997

5

Involvement of vascular endothelial growth factor and urokinase-type plasminogen activator receptor in microvessel invasion in human colorectal cancers

Shinji Nakata, Ken-ichi Ito, Minoru Fujimori, Kiyoshi Shingū, Shoji Kajikawa, Wataru Adachi, Ikuo Matsuyama, Shin-ichi Tsuchiya, Michihiko Kuwano, Jun Amano

Journal:

International Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 538 KB

english, 1998

6

Enhanced coexpression of YB-1 and DNA topoisomerase II α genes in human colorectal carcinomas

Kazunori Shibao, Hiroshi Takano, Yoshifumi Nakayama, Keisuke Okazaki, Naoki Nagata, Hiroto Izumi, Takeshi Uchiumi, Michihiko Kuwano, Kimitoshi Kohno, Hideaki Itoh

Journal:

International Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 738 KB

english, 1999

7

Macrophage infiltration correlates with tumor stage and angiogenesis in human malignant melanoma: Possible involvement of TNFα and IL-1α

Hitoe Torisu, Mayumi Ono, Hiromaro Kiryu, Masutaka Furue, Yasukazu Ohmoto, Juichiro Nakayama, Yasuhiko Nishioka, Saburo Sone, Michihiko Kuwano

Journal:

International Journal of Cancer

Year:

2000

Language:

english

File:

PDF, 307 KB

english, 2000

8

Alu-associated interstitial deletions and chromosomal re-arrangement in 2 human multidrug-resistant cell lines

Taishi Harada, Jun Nagayama, Kimitoshi Kohno, Lyn A. Mickley, Tito Fojo, Michihiko Kuwano, Morimasa Wada

Journal:

International Journal of Cancer

Year:

2000

Language:

english

File:

PDF, 136 KB

english, 2000

9

Contribution of P-glycoprotein to bunitrolol efflux across blood–brain barrier

Jo Matsuzaki, Chika Yamamoto, Tetsuo Miyama, Hitomi Takanaga, Hirotami Matsuo, Hitoshi Ishizuka, Yukinori Kawahara, Michihiko Kuwano, Mikihiko Naito, Takashi Tsuruo, Yasufumi Sawada

Journal:

Biopharmaceutics & Drug Disposition

Year:

1999

Language:

english

File:

PDF, 143 KB

english, 1999

10

Cellular vitamin A-binding proteins in liver tumors and adjacent tissues

Kiyonobu Ikezaki, Hitoshi Ueda, Toshihiko Koyanogi, Michihiko Kuwano, Kenji Ando, Seiya Sato, Kenji Takenaka, Kiyoshi Inokuchi

Journal:

Year:

1985

Language:

english

File:

PDF, 436 KB

english, 1985

11

Cellular retinol-binding proteins in head and neck tumors and their adjacent tissues

Tomoko Yanagita, Sohtaro Komiyama, Michihiko Kuwano

Journal:

Year:

1986

Language:

english

File:

PDF, 453 KB

english, 1986

12

Establishment of tumor cell lines from a patient with head and neck cancer and their different sensitivities to anti-cancer agents

Sohtaro Komiyama, Katsuko Matsui, Shohji Kudoh, Ichiro Nogae, Yuichiro Kuratomi, Yoshio Saburi, Kuni-Ichi Asoh, Kimitoshi Kohno, Michihiko Kuwano

Journal:

Year:

1989

Language:

english

File:

PDF, 660 KB

english, 1989

13

Expression of glutathione s-transferasepi and sensitivity of human gastric cancer cells to cisplatin

Toshiro Okuyama, Yoshihiko Maehara, Kazuya Endo, Hideo Baba, Yosuke Adachi, Michihiko Kuwano, Keizo Sugimachi

Journal:

Year:

1994

Language:

english

File:

PDF, 981 KB

english, 1994

14

The pleiotropic functions of the Y-box-binding protein, YB-1

Kimitoshi Kohno, Hiroto Izumi, Takeshi Uchiumi, Megumi Ashizuka, Michihiko Kuwano

Journal:

Year:

2003

Language:

english

File:

PDF, 215 KB

english, 2003

15

ChemInform Abstract: Structure of a Novel Multidrug Resistance Modulator, Irciniasulfonic Acid, Isolated from a Marine Sponge, Ircinia sp.

Ayako Kawakami, Tomofumi Miyamoto, Ryuichi Higuchi, Takeshi Uchiumi, Michihiko Kuwano, Rob W. M. Van Soest

Journal:

Year:

2001

File:

PDF, 27 KB

2001

16

1,3-Dimethylisoguaninium, an Antiangiogenic Purine Analogue from the Sponge Amphimedon paraviridis.

Sei-Joon Jeong, Masanori Inagaki, Ryuichi Higuchi, Tomofumi Miyamoto, Mayumi Ono, Michihiko Kuwano, Rob W. M. Van Soest

Journal:

Year:

2003

File:

PDF, 58 KB

2003

17

N-myc downstream-regulated gene 1 expression in injured sciatic nerves

Kazuho Hirata, Katsuaki Masuda, Wataru Morikawa, Jian-Wen He, Akio Kuraoka, Michihiko Kuwano, Masaru Kawabuchi

Journal:

Year:

2004

Language:

english

File:

PDF, 2.84 MB

english, 2004

18

Interleukin-1β represses MRP2 gene expression through inactivation of interferon regulatory factor 3 in HepG2 cells

Keiji Hisaeda, Akihiko Inokuchi, Takanori Nakamura, Yukihide Iwamoto, Kimitoshi Kohno, Michihiko Kuwano, Takeshi Uchiumi

Journal:

Year:

2004

Language:

english

File:

PDF, 339 KB

english, 2004

19

Enhanced expression of thrombospondin-1 and hypovascularity in human cholangiocarcinoma

Naoyuki Kawahara, Mayumi Ono, Ken-ichi Taguchi, Masahiro Okamoto, Mitsuo Shimada, Kenji Takenaka, Kenshi Hayashi, Dean F. Mosher, Keizo Sugimachi, Masazumi Tsuneyoshi, Michihiko Kuwano

Journal:

Year:

1998

Language:

english

File:

PDF, 596 KB

english, 1998

20

The human multidrug resistance protein 2 gene: Functional characterization of the 5′-flanking region and expression in hepatic cells

Toshiya Tanaka, Takeshi Uchiumi, Eiji Hinoshita, Akihiko Inokuchi, Satoshi Toh, Morimasa Wada, Hiroshi Takano, Kimitoshi Kohno, Michihiko Kuwano

Journal:

Year:

1999

Language:

english

File:

PDF, 207 KB

english, 1999

21

Increased expression of multidrug resistance-associated proteins in bladder cancer during clinical course and drug resistance to doxorubicin

Yasuhiro Tada, Morimasa Wada, Toshiro Migita, Jun Nagayama, Eiji Hinoshita, Yasushi Mochida, Yoshihiko Maehara, Masazumi Tsuneyoshi, Michihiko Kuwano, Seiji Naito

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 787 KB

english, 2002

22

Downregulation of Cap43 gene by von Hippel-Lindau tumor suppressor protein in human renal cancer cells

Katsuaki Masuda, Mayumi Ono, Masahiro Okamoto, Wataru Morikawa, Michihiro Otsubo, Toshiro Migita, Masazumi Tsuneyoshi, Heiwa Okuda, Taro Shuin, Seiji Naito, Michihiko Kuwano

Journal:

International Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 714 KB

english, 2003

23

ATP-binding cassette superfamily transporter gene expression in human soft tissue sarcomas

Yoshinao Oda, Tsuyoshi Saito, Naomi Tateishi, Yoshihiro Ohishi, Sadafumi Tamiya, Hidetaka Yamamoto, Ryohei Yokoyama, Takeshi Uchiumi, Yukihide Iwamoto, Michihiko Kuwano, Masazumi Tsuneyoshi

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 509 KB

english, 2005

24

A mouse leukemia cell mutant resistant to blasticidin s

Michihiko Kuwano, Katsuko Matsui, Kenji Takenaka, Shin-Ichi Akiyama, Hideya Endo

Journal:

International Journal of Cancer

Year:

1977

Language:

english

File:

PDF, 524 KB

english, 1977

25

Anti-angiogenic activity of arachidonic acid metabolism inhibitors in angiogenesis model systems involving human microvascular endothelial cells and neovascularization in mice

Ken-Ichi Ito, Mayumi Ono, Tatsuya Abe, Michihiko Kuwano, Akio Morimoto, Kimitoshi Kohno, Teruaki Mori, Mika Tomita, Akira Sugenoya, Tetsuro Nishihira

Journal:

International Journal of Cancer

Year:

1993

Language:

english

File:

PDF, 929 KB

english, 1993

26

Possible involvement of multidrug-resistance-associated protein (MRP) gene expression in spontaneous drug resistance to vincristine, etoposide and adriamycin in human glioma cells

Shuji Hasegawa, Ken Taniguchi, Akira Yokomizo, Takashi Kuwano, Mayumi Ono, Temaki Mori, Shigeaki Hori, Kimitoshi Kohno, Michihiko Kuwano

Journal:

International Journal of Cancer

Year:

1994

Language:

english

File:

PDF, 671 KB

english, 1994

27

Amphotericin B resistance is recessive in Chinese hamster hybrid cells

Katsuhiko Hidaka, Shin-Ichi Akiyama, Michihiko Kuwano

Journal:

Journal of Cellular Physiology

Year:

1981

Language:

english

File:

PDF, 486 KB

english, 1981

28

Isolation and preliminary characterization of bleomycin-resistant mutants from Chinese hamster ovary cells

Shin-Ichi Akiyama, Michihiko Kuwano

Journal:

Journal of Cellular Physiology

Year:

1981

Language:

english

File:

PDF, 511 KB

english, 1981

29

Isolation and characterization of vitamin A-sensitive chinese hamster lung cell lines

Kiyonobu Ikezaki, Shin-Ichi Akiyama, Mitsuo Nakamura, Sohtaro Komiyama, Michihiko Kuwano

Journal:

Journal of Cellular Physiology

Year:

1983

Language:

english

File:

PDF, 1.08 MB

english, 1983

30

Chinese hamster ovary cell variants resistant to monensin, an ionophoric antibiotic. II. Growth requirement for insulin and altered insulin-receptor activity

Yasufumi Sato, Mayumi Ono, Ryosaburo Takaki, Michihiko Kuwano

Journal:

Journal of Cellular Physiology

Year:

1984

Language:

english

File:

PDF, 668 KB

english, 1984

31

Chinese hamster ovary cell variants resistant to monensin, an ionophoric antibiotic. I. Isolation and altered endocytosis of ricin

Mayumi Ono, Hisae Yamato, Miho Ando, Michihiko Kuwano

Journal:

Journal of Cellular Physiology

Year:

1984

Language:

english

File:

PDF, 567 KB

english, 1984

32

Defective endocytosis of low-density lipoprotein in monensin-resistant mutants of the mouse Balb/3T3 cell line

Kichinobu Tomita, Mayumi Ono, Akinori Masuda, Shin-Ichi Akiyama, Michihiko Kuwano

Journal:

Journal of Cellular Physiology

Year:

1985

Language:

english

File:

PDF, 836 KB

english, 1985

33

Mouse Balb/c3T3 cell mutant with low epidermal growth factor receptor activity: Induction of stable anchorage-independent growth by transforming growth factor β

Yuichiro Kuratomi, Mayumi Ono, Chie Yasutake, Masasumi Mawatari, Michihiko Kuwano

Journal:

Journal of Cellular Physiology

Year:

1987

Language:

english

File:

PDF, 914 KB

english, 1987

34

Insulin receptor and altered glucose transport in a monensin-resistant mutant of Chinese hamster ovary cell

Tadashi Seguchi, Akihiko Yoshimura, Mayumi Ono, Satoshi Shite, Michihiro Kasahara, Yosuke Ebina, William J. Rutter, Michihiko Kuwano

Journal:

Journal of Cellular Physiology

Year:

1989

Language:

english

File:

PDF, 802 KB

english, 1989

35

Decreased response to epidermal growth factor during cellular senescence in cultured human microvascular endothelial cells

Takao Matsuda, Kazuki Okamura, Yasufumi Sato, Akio Morimoto, Mayumi Ono, Kimitoshi Kohno, Michihiko Kuwano

Journal:

Journal of Cellular Physiology

Year:

1992

Language:

english

File:

PDF, 935 KB

english, 1992

36

Expression of tissue-type plasminogen activator and its inhibitor couples with development of capillary network by human microvascular endothelial cells on matrigel

Ken-Ichi Ito, Masahiro Ryuto, Shin Ushiro, Mayumi Ono, Akira Sugenoya, Akio Kuraoka, Yosaburo Shibata, Michihiko Kuwano

Journal:

Journal of Cellular Physiology

Year:

1995

Language:

english

File:

PDF, 1.38 MB

english, 1995

37

Synthesis of 2-phenylimidazo[2,1-b]benzothiazole derivatives as modulators of multidrug resistance for tumor cells

Shigeyuki Tasaka, Hirokazu Tanabe, Yoshiyuki Sasaki, Toshiki Machida, Mayumi Iino, Akira Kiue, Seiji Naito, Michihiko Kuwano

Journal:

Journal of Heterocyclic Chemistry

Year:

1997

File:

PDF, 360 KB

1997

38

Structure of a novel multidrug resistance modulator, irciniasulfonic acid, isolated from a marine sponge, Ircinia sp.

Ayako Kawakami, Tomofumi Miyamoto, Ryuichi Higuchi, Takeshi Uchiumi, Michihiko Kuwano, Rob W.M Van Soest

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 65 KB

english, 2001

39

Synthesis and structure–activity analysis of novel dihydropyridine derivatives to overcome multidrug resistance

Shigeyuki Tasaka, Hiromasa Ohmori, Noriaki Gomi, Mayumi Iino, Tosiki Machida, Akira Kiue, Seiji Naito, Michihiko Kuwano

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 129 KB

english, 2001

40

Newly synthesized dihydropyridine derivatives as modulators of P-Glycoprotein-mediated multidrug resistance

Hirokazu Tanabe, Shigeyuki Tasaka, Hiromasa Ohmori, Noriaki Gomi, Yoshiyuki Sasaki, Toshiki Machida, Mayumi Iino, Akira Kiue, Seiji Naito, Michihiko Kuwano

Journal:

Bioorganic & Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 179 KB

english, 1998

41

Nuclear expression of Y-box-binding protein-1 correlates with P-glycoprotein and topoisomerase II alpha expression, and with poor prognosis in synovial sarcoma

Yoshinao Oda, Yoshihiro Ohishi, Tsuyoshi Saito, Eiji Hinoshita, Takeshi Uchiumi, Naoko Kinukawa, Yukihide Iwamoto, Kimitoshi Kohno, Michihiko Kuwano, Masazumi Tsuneyoshi

Journal:

The Journal of Pathology

Year:

2003

Language:

english

File:

PDF, 345 KB

english, 2003

42

Anin vitroinvasion model for human renal cell carcinoma cell lines mimicking their metastatic abilities

Yoshifumi Nakayama, Seiji Naito, Masahiro Ryuto, Yasuaki Hata, Mayumi Ono, Katsuo Sueishi, Sohtaro Komiyama, Hideaki Roh, Michihiko Kuwano

Journal:

Clinical and Experimental Metastasis

Year:

1996

Language:

english

File:

PDF, 970 KB

english, 1996

43

Initialtrpoperon sequence inEscherichia coliis transcribed without coupling to translation

Yasunobu Kano, Michihiko Kuwano, Fumio Imamoto

Journal:

Molecular Genetics and Genomics

Year:

1976

Language:

english

File:

PDF, 869 KB

english, 1976

44

Genetic analysis of a mutation affecting ribosomal protein S1 inEscherichia coli

Mayumi Ono, Michihiko Kuwano, Shoji Mizushima

Journal:

Molecular Genetics and Genomics

Year:

1979

Language:

english

File:

PDF, 981 KB

english, 1979

45

Gene affecting longevity of messenger RNA: A mutant ofEscherichia coliwith altered mRNA stability

Michihiko Kuwano, Mayumi Ono, Hideya Endo, Katsuji Hori, Kunihiko Nakamura, Yukinori Hirota, Yoshinari Ohnishi

Journal:

Molecular Genetics and Genomics

Year:

1977

Language:

english

File:

PDF, 680 KB

english, 1977

46

Genetic analysis of mutations affecting ribonuclease II inEscherichia coli

Mayumi Ono, Michihiko Kuwano, Takashi Horiuchi

Journal:

Molecular Genetics and Genomics

Year:

1977

Language:

english

File:

PDF, 322 KB

english, 1977

47

Expression of 72 kDa type IV collagenase and invasion activity of human glioma cells

Tatsuya Abe, Teruaki Mori, Kimitoshi Kohno, Motoharu Sciki, Taro Hayakawa, Howard G. Welgus, Shigeaki Hori, Michihiko Kuwano

Journal:

Clinical and Experimental Metastasis

Year:

1994

Language:

english

File:

PDF, 998 KB

english, 1994

48

Maintenance of hypomethylation status and preferential expression of exogenous humanMDR1/PGY1gene in mouse L cells by YAC mediated transfer

Hitoshi Kusaba, Masaharu Nakayama, Taishi Harada, Kiyoyuki Torigoe, Eric D. Green, Stephen W. Scherer, Kimitoshi Kohno, Michihiko Kuwano, Morimasa Wada

Journal:

Somatic Cell and Molecular Genetics

Year:

1997

Language:

english

File:

PDF, 1.83 MB

english, 1997

49

Expression of ERCC1 and class III β-tubulin in non-small cell lung cancer patients treated with a combination of cisplatin/docetaxel and concurrent thoracic irradiation

Koichi Azuma, Tetsuro Sasada, Akihiko Kawahara, Satoshi Hattori, Takashi Kinoshita, Sinzo Takamori, Masao Ichiki, Youhei Imamura, Jiro Ikeda, Masayoshi Kage, Michihiko Kuwano, Hisamichi Aizawa

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2009

Language:

english

File:

PDF, 449 KB

english, 2009

50

Angiogenesis as a new target for cancer treatment

M. Ono, Hiroto Izumi, Shigeo Yoshida, Daisuke Goto, Sei-ichiro Jimi, Naoyuki Kawahara, Tadahisa Shono, Shin Ushiro, Masahiro Ryuto, Kimitoshi Kohno, Yasafumi Sato, Michihiko Kuwano

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1996

Language:

english

File:

PDF, 106 KB

english, 1996

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